Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938249 | 0.82 | EPHA2 (0.48) | EPHA2 | |
| SCHEMBL28938268 | 0.82 | EPHA2 (0.44) | EPHA2CCNT1CDK9 | |
| SCHEMBL28938246 | 0.80 | EPHA2 (0.42) | EPHA2 | |
| SCHEMBL28938270 | 0.78 | EPHA2 (0.42) | EPHA2 | |
| SCHEMBL28946210 | 0.77 | EGFR (0.51) | EPHA2 | |
| SCHEMBL28938261 | 0.72 | MEN1 (0.53) | — | |
| SCHEMBL28938252 | 0.70 | NTRK1 (0.50) | — | |
| SCHEMBL28672738 | 0.70 | — | — | |
| SCHEMBL4890627 | 0.69 | EPHA2 (0.71) | EPHA2 | |
| SCHEMBL25173543 | 0.68 | SLC6A3 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457260-B | N-heterocyclic aryl quinazoline-4-amine compound and preparation method thereof | 江苏食品药品职业技术学院 | 2023-01-17 | — | — | CN | disclosed |
| CN-112457260-A | N-heterocyclic aryl quinazoline-4-amine compound and preparation method thereof | 江苏食品药品职业技术学院 | 2021-03-09 | — | — | CN | disclosed |