Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22657419 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL28726084 | 0.85 | THRB (0.51) | THRBTHRA | |
| SCHEMBL28726186 | 0.84 | THRB (0.50) | THRBTHRA | |
| SCHEMBL13044633 | 0.83 | THRB (0.70) | THRBTHRA | |
| SCHEMBL13381691 | 0.82 | THRB (0.60) | THRBTHRA | |
| SCHEMBL29542258 | 0.81 | THRB (0.51) | THRBTHRA | |
| SCHEMBL281842 | 0.81 | THRB (0.51) | THRBTHRA | |
| SCHEMBL22657583 | 0.79 | EPHX2 (0.39) | — | |
| SCHEMBL29534662 | 0.79 | EPHX2 (0.39) | — | |
| SCHEMBL13703170 | 0.74 | THRB (0.59) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450266-B | Novel thyromimetic agents with biphenylmethane scaffolds and uses thereof | 国际药物开发学会有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114450266-A | Novel thyromimetic drug with biphenylmethane scaffold and uses thereof | 国际药物开发学会有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3969436-A1 | NOVEL THYROMIMETICS WITH A BIPHENYLMETHANE SCAFFOLD AND THEIR USE | International Society for Drug Development S.r.l. (IT) | 2022-03-23 | — | — | EP | disclosed |