Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564782 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL5737140 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL10601540 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL6682171 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL10863585 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL8509012 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL9697706 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL6686137 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL6065358 | 0.91 | LIPG (0.62) | LIPGNR1H2NR1H3THRBBID | |
| SCHEMBL1372464 | 0.87 | LIPG (0.59) | LIPGNR1H2NR1H3THRBBID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269432-A | As P2X3Aminoquinazoline derivatives as inhibitors | 奇斯药制品公司 | 2022-04-01 | — | — | CN | disclosed |