Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.58 |
| ▸ | INSR | P06213 | 2/20 | 0.58 |
| ▸ | IGF1R | P08069 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942225 | 0.91 | EGFR (0.67) | EGFRALKINSRIGF1R | |
| SCHEMBL22942144 | 0.90 | INSR (0.69) | EGFRALKINSRIGF1R | |
| SCHEMBL22942870 | 0.90 | EGFR (0.66) | EGFRALKINSRIGF1R | |
| SCHEMBL29559850 | 0.90 | EGFR (0.66) | EGFRALKINSRIGF1R | |
| SCHEMBL22942164 | 0.89 | EGFR (0.60) | EGFRALKINSRIGF1R | |
| SCHEMBL24940084 | 0.89 | EGFR (0.63) | EGFRALKINSRIGF1R | |
| SCHEMBL24816789 | 0.89 | EGFR (0.65) | EGFRALKINSRIGF1R | |
| SCHEMBL30105862 | 0.89 | EGFR (0.63) | EGFRALKINSRIGF1R | |
| SCHEMBL24940076 | 0.89 | EGFR (0.69) | EGFRALKINSRIGF1R | |
| SCHEMBL30105864 | 0.89 | EGFR (0.69) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114430740-A | EGFR inhibitor, composition and preparation method thereof | 贝达药业股份有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-114430740-B | EGFR inhibitors, compositions and methods of making the same | 贝达药业股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-114430740-A | EGFR inhibitor, composition and preparation method thereof | 贝达药业股份有限公司 | 2022-05-03 | — | — | CN | disclosed |