Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364335 | 0.70 | ADORA2A (0.60) | ADORA2AADORA2BADORA1 | |
| SCHEMBL15689328 | 0.70 | ADORA2A (0.65) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22326733 | 0.65 | ADORA2A (0.62) | ADORA2AADORA2BADORA1 | |
| SCHEMBL10121588 | 0.65 | ADORA2A (0.38) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4379586 | 0.63 | ADORA1 (0.56) | ADORA2AADORA1PIK3CD | |
| SCHEMBL9726980 | 0.63 | PI4KA (0.45) | PIK3CD | |
| SCHEMBL22509851 | 0.62 | ACACB (0.44) | — | |
| SCHEMBL10336097 | 0.62 | FLT4 (0.46) | ADORA2AADORA1 | |
| SCHEMBL13082054 | 0.62 | TP53 (0.50) | — | |
| SCHEMBL9503851 | 0.62 | FLT4 (0.49) | ADORA2AADORA2BADORA1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524815-B | 8-alkoxypurine derivative and preparation method and application thereof | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114524815-A | 8-alkoxy purine derivative and preparation method and application thereof | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |