Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 9/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30161982 | 0.83 | RPS6KB1 (0.54) | GPR119RPS6KB1AKT1MAP4K4 | |
| SCHEMBL28939454 | 0.83 | RPS6KB1 (0.54) | GPR119RPS6KB1AKT1MAP4K4 | |
| SCHEMBL19000161 | 0.81 | GPR119 (0.52) | GPR119NR1H2NR1H3EGLN2RET | |
| SCHEMBL5128070 | 0.79 | GPR119 (0.49) | GPR119NR1H2NR1H3EGLN2MAP4K4 | |
| SCHEMBL21645241 | 0.77 | GPR119 (0.37) | GPR119RPS6KB1AKT1 | |
| SCHEMBL18980252 | 0.76 | RPS6KB1 (0.48) | RPS6KB1AKT1 | |
| SCHEMBL18980545 | 0.76 | EIF2AK4 (0.42) | RPS6KB1AKT1RETMAP4K4 | |
| SCHEMBL3922803 | 0.75 | GPR119 (0.48) | GPR119NR1H2NR1H3EGLN2RET | |
| SCHEMBL26651056 | 0.75 | GPR119 (0.44) | GPR119NR1H2NR1H3EGLN2RET | |
| SCHEMBL652792 | 0.75 | GRM5 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485025-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-16 | — | — | CN | disclosed |