Pyrimidine

Pyrimidine

SCHEMBL28939712

CCCCCNC(N)=O.c1cncnc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.47
EPHX1 P07099 9/20 0.46
KDM4E B2RXH2 1/20 0.44
CASP2 P42575 1/20 0.42
ALOX12 P18054 1/20 0.41
DPP7 Q9UHL4 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
FAAH O00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL23086233 0.85 EPHX1 (0.56) NAAAEPHX1CASP2DPP7ALDH1A1
Benzene SCHEMBL28591011 0.83 EPHX1 (0.59) NAAAEPHX1CASP2ALDH1A1HTT
SCHEMBL28947 0.83
SCHEMBL8007143 0.83 EPHX1 (0.62) NAAAEPHX1CASP2DPP7
Pyrimidine SCHEMBL27454358 0.83 NAAA (0.41) NAAAEPHX1KDM4ECASP2ALOX12
SCHEMBL19468513 0.81 EPHX1 (0.67) NAAAEPHX1CASP2DPP7
SCHEMBL19468503 0.81 EPHX1 (0.67) NAAAEPHX1CASP2DPP7
SCHEMBL2185171 0.81 EPHX1 (0.67) NAAAEPHX1CASP2DPP7
SCHEMBL76613 0.81 EPHX1 (0.67) NAAAEPHX1CASP2DPP7
SCHEMBL19468457 0.81 EPHX1 (0.67) NAAAEPHX1CASP2DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364666-A Substituted N-phenyl-N-semicarbazides pyrimidines and salts thereof and their use as herbicides 拜耳公司 2022-04-15 CN disclosed