Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800582 | 1.00 | EGFR (0.52) | EGFRMKNK1MKNK2CDC7FLT3 | |
| SCHEMBL5750318 | 0.85 | CDC7 (0.60) | EGFRMKNK1MKNK2CDC7DYRK1A | |
| SCHEMBL29870510 | 0.85 | CDC7 (0.60) | EGFRMKNK1MKNK2CDC7DYRK1A | |
| Hydrochloric Acid SCHEMBL5749287 | 0.84 | CDC7 (0.59) | EGFRMKNK1MKNK2CDC7DYRK1A | |
| SCHEMBL28987594 | 0.82 | CDK5 (0.51) | EGFRMKNK1MKNK2CDC7FLT3 | |
| SCHEMBL29419125 | 0.82 | MKNK1 (0.50) | EGFRMKNK1MKNK2CDC7FLT3 | |
| SCHEMBL30337182 | 0.82 | CDK5 (0.51) | EGFRMKNK1MKNK2CDC7FLT3 | |
| SCHEMBL5096322 | 0.82 | MKNK1 (0.50) | EGFRMKNK1MKNK2CDC7FLT3 | |
| SCHEMBL30219257 | 0.81 | DYRK1B (0.54) | EGFRMKNK1MKNK2FLT3DYRK1A | |
| SCHEMBL28927716 | 0.80 | EGFR (0.53) | EGFRMKNK1MKNK2FLT3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651800-B | Preparation method of oxitinib mesylate | 山东铂源药业股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-113651800-A | Preparation method of oxitinib mesylate | 山东铂源药业有限公司 | 2021-11-16 | — | — | CN | disclosed |