Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987594 | 1.00 | CDK5 (0.51) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL28939744 | 0.82 | EGFR (0.52) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL29419125 | 0.82 | MKNK1 (0.50) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL5096322 | 0.82 | MKNK1 (0.50) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL5750318 | 0.82 | CDC7 (0.60) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL29800582 | 0.82 | EGFR (0.52) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL29870510 | 0.82 | CDC7 (0.60) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL17490423 | 0.82 | MKNK1 (0.47) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| Hydrochloric Acid SCHEMBL5749287 | 0.81 | CDC7 (0.59) | CDK5CDK5R1MKNK1MKNK2EGFR | |
| SCHEMBL30219257 | 0.81 | DYRK1B (0.54) | CDK5CDK5R1MKNK1MKNK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |