Esculin

Esculin

SCHEMBL2894

O=c1ccc2cc(OC3OC(CO)C(O)C(O)C3O)c(O)cc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
HPGD P15428 6/20 1.00
HSD17B10 Q99714 6/20 1.00
KDM4E B2RXH2 5/20 1.00
CASP1 P29466 5/20 1.00
CASP7 P55210 5/20 1.00
GAA P10253 5/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
GLA P06280 3/20 1.00
AMY1A P0DUB6 2/20 1.00
CYP2C19 P33261 1/20 1.00
STAT6 P42226 1/20 1.00
ERAP1 Q9NZ08 4/20 0.98
CA12 O43570 6/20 0.78
CA9 Q16790 6/20 0.78
CA1 P00915 5/20 0.78
CA7 P43166 3/20 0.78
CA13 Q8N1Q1 3/20 0.78
L3MBTL1 Q9Y468 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Esculin SCHEMBL1706315 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL7537406 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL8035285 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL29350403 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL8183298 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL13096298 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL19756246 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL20179973 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL2893 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1
Esculin SCHEMBL13713835 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10KDM4ECASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9757 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139221-A1 Akkermansia muciniphila MG784 for alleviating constipation,promoting defecation, improving intestinal barrier function and intestinal immunity, and its uses MOMS GARDEN GMBH (DE) 2026-05-21 US claimed
CN-122055161-A Microbiota Restoration Therapy (MRT) compositions and methods of administration 辉凌微生物组有限公司 2026-05-15 CN claimed
EP-4728046-A1 LACTOBACILLUS SUANTSAII STRAIN AND USE THEREOF Univer-Product Termelo És Kereskedelmi Zártköruen Muködo Részvénytársaság (HU) 2026-04-22 EP claimed
WO-2025054086-A9 MICROBIOTA RESTORATION THERAPY (MRT) COMPOSITIONS AND METHODS OF ADMINISTRATION Ferring Microbiome Inc. (US) 2026-03-05 WO claimed
EP-4581045-A1 BIFIDOBACTERIUM ADOLESCENTIS STRAINS, METHODS AND USES THEREOF FOR STARCH DEGRADATION AND MODIFYING GUT FLORA IN NON-HUMAN MAMMALS DSM IP Assets B.V. (NL) 2025-07-09 EP claimed
CN-120114523-A Lipase inhibitor with specific structure and preparation method and application thereof 中国海洋大学 2025-06-10 CN claimed
CN-120041327-A Bacillus proximilis and application thereof 湖北省农业科学院植保土肥研究所 2025-05-27 CN claimed
EP-3967315-B1 AKKERMANSIA MUCINIPHILA FOR TREATING CANCER UNIV CATHOLIQUE LOUVAIN (BE) 2025-05-14 EP claimed
EP-3943093-B1 USE OF PASTEURIZED AKKERMANSIA FOR TREATING CANCER UNIV CATHOLIQUE LOUVAIN (BE) 2025-05-07 EP claimed
EP-3862010-B1 USE OF AKKERMANSIA MUCINIPHILA FOR PROMOTING WEIGHT LOSS UNIV CATHOLIQUE LOUVAIN (BE) 2025-05-07 EP claimed
EP-0020678-A1 METHOD FOR SEWAGE TREATMENT WITH BACTERIA. BODENRADER B J 1981-01-07 EP claimed
US-4238483-A Antimicrobial compositions of matter and a process for preparing antimicrobial compositions of matter from naturally occurring flavanoid glycosides RUSH-HAMPTON INDUSTRIES, INC. 1980-12-09 US claimed
US-4235963-A Sampling and identifying apparatus and method HANSEN JOE C 1980-11-25 US claimed
WO-1980002282-A1 METHOD FOR BACTERIOLOGICAL TREATMENT OF MANURE AND HIGH BOD INDUSTRIAL WASTES BODENRADER B 1980-10-30 WO claimed
US-4214985-A ADDITION OF A LACTOBACILLUS AND A CARBOHYDRATE BODENRADER B J 1980-07-29 US claimed
US-4211772-A CAPILLARIES, DIABETIC CATARACTS LABORATOIRES SARGET (FR) 1980-07-08 US claimed
WO-1980001067-A1 METHOD FOR SEWAGE TREATMENT WITH BACTERIA BODENRADER B 1980-05-29 WO claimed
US-4173515-A FERRIC AMMONIUM CITRATE, ESCULIN HYDROLYSATE, ANTIBIOTIC INHIBITOR MCDONNELL DOUGLAS CORPORATION (US) 1979-11-06 US claimed
US-4133875-A Method of controlling dental caries with streptococcus mutans mutant strains FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) 1979-01-09 US claimed
US-4010078-A MULTICOMPARTMENT, CULTURES TAYLOR WELTON I 1977-03-01 US claimed