SCHEMBL28940337

SCHEMBL28940337

OCCN(CO)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
GAA P10253 1/20 0.45
KDM4E B2RXH2 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TSHR P16473 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.39
PABPC1 P11940 1/20 0.38
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
CYP2D6 P10635 1/20 0.37
BLM P54132 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
NPC1 O15118 1/20 0.37
MITF O75030 1/20 0.37
NSD2 O96028 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78451 0.90 KDM4E (0.46) ALDH1A1GAAKDM4EL3MBTL1TSHR
Bromide SCHEMBL11628834 0.88 KDM4E (0.44) ALDH1A1GAAKDM4EL3MBTL1TSHR
Hydrochloric Acid SCHEMBL28957289 0.88 KDM4E (0.48) ALDH1A1GAAKDM4EL3MBTL1TSHR
Ammonia Solution, Strong SCHEMBL28490308 0.88 KDM4E (0.44) ALDH1A1GAAKDM4EL3MBTL1TSHR
SCHEMBL23468470 0.86 MEN1 (0.40) ALDH1A1GAAKDM4EL3MBTL1TSHR
SCHEMBL487259 0.85 TSHR (0.44) ALDH1A1GAAL3MBTL1TSHRMEN1
Boric Acid SCHEMBL30555202 0.84 KDM4E (0.42) ALDH1A1GAAKDM4EL3MBTL1TSHR
SCHEMBL547493 0.83 ALDH1A1 (0.51) ALDH1A1GAAKDM4EL3MBTL1TSHR
Hydrochloric Acid SCHEMBL28375845 0.82 TSHR (0.43) ALDH1A1GAAKDM4EL3MBTL1TSHR
SCHEMBL14731921 0.82 KDM4E (0.41) ALDH1A1GAAKDM4EL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113666846-A Synthetic method of saxagliptin intermediate 济南立德医药技术有限公司 2021-11-19 CN disclosed