Benzo[E]Pyrene

Benzo[E]Pyrene

SCHEMBL28940487

Oc1ccccc1.c1ccc2c(c1)c1cccc3ccc4cccc2c4c31

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.73
ALDH1A1 P00352 4/20 0.73
HSD17B10 Q99714 4/20 0.73
HPGD P15428 3/20 0.73
THRB P10828 3/20 0.73
ERBB2 P04626 1/20 0.52
FYN P06241 1/20 0.52
MAOA P21397 1/20 0.52
ACHE P22303 1/20 0.52
AHR P35869 1/20 0.52
TDP1 Q9NUW8 4/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
GLA P06280 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
HPRT1 P00492 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL11553889 0.91 ALDH1A1 (0.56) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Pyrene SCHEMBL28023143 0.85 CYP1A2 (0.61) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Pyrene SCHEMBL27626839 0.85 CYP1A2 (0.61) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[E]Pyrene SCHEMBL24020 0.85 ALDH1A1 (1.00) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[E]Pyrene SCHEMBL29432647 0.85 ALDH1A1 (1.00) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[E]Pyrene SCHEMBL4983272 0.85 ALDH1A1 (1.00) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[E]Pyrene SCHEMBL29357057 0.85 ALDH1A1 (1.00) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[Def]Chrysene SCHEMBL5135124 0.85 CYP1A2 (0.79) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[E]Pyrene SCHEMBL1179468 0.83 ALDH1A1 (0.94) CYP1A2ALDH1A1HSD17B10HPGDTHRB
Benzo[E]Pyrene SCHEMBL28840328 0.83 ALDH1A1 (0.94) CYP1A2ALDH1A1HSD17B10HPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109072066-B Light control material, light control film, and light control laminate 积水化学工业株式会社 2022-05-24 CN disclosed