SCHEMBL28940593

SCHEMBL28940593

O=C(Cc1ccc(Cl)cc1Cl)Cc1ccc(Cl)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.54
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
MAPK1 P28482 1/20 0.52
CYP2C19 P33261 1/20 0.52
ERCC1 P07992 4/20 0.51
ERCC4 Q92889 4/20 0.51
P2RX7 Q99572 1/20 0.51
GGPS1 O95749 1/20 0.50
GALR3 O60755 1/20 0.50
NR2F2 P24468 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31204467 0.90 IDO1 (0.53) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL3017863 0.90 MAPK1 (0.52) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL2211442 0.90 IDO1 (0.53) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL20595771 0.88 IDO1 (0.49) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL2642684 0.88 IDO1 (0.47) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL9978814 0.88 ERCC1 (0.49) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11046383 0.88 TDP1 (0.49) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11549706 0.88 HPGD (0.61) ERCC1ERCC4TDP1L3MBTL1TP53
Hydrochloric Acid SCHEMBL23391445 0.87 IDO1 (0.51) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11311719 0.87 ALDH1A1 (0.50) IDO1ERCC1ERCC4P2RX7GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115626899-A Penconazole production method 江苏禾本生化有限公司 2023-01-20 CN disclosed