Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743818 | 0.87 | NAA50 (0.32) | NAA50 | |
| SCHEMBL1275276 | 0.83 | USP30 (0.43) | NR1H2NR1H3UCHL1GPR119USP30 | |
| SCHEMBL1275274 | 0.83 | USP30 (0.43) | NR1H2NR1H3UCHL1GPR119USP30 | |
| SCHEMBL10077030 | 0.83 | NAA50 (0.40) | NR1H2NR1H3UCHL1GPR119USP30 | |
| SCHEMBL28743820 | 0.81 | NR1H2 (0.57) | NR1H2NR1H3 | |
| SCHEMBL1273394 | 0.81 | NR1H2 (0.40) | NR1H2NR1H3UCHL1GPR119USP30 | |
| SCHEMBL1273147 | 0.81 | NR1H2 (0.40) | NR1H2NR1H3UCHL1GPR119USP30 | |
| SCHEMBL1273270 | 0.81 | NR1H2 (0.40) | NR1H2NR1H3UCHL1GPR119USP30 | |
| SCHEMBL28743783 | 0.80 | NR1H2 (0.42) | NR1H2NR1H3UCHL1USP30NAA50 | |
| SCHEMBL1273532 | 0.79 | NR1H2 (0.41) | NR1H2NR1H3UCHL1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705191-B | IAP inhibitors and their use in medicine | 广东东阳光药业有限公司 | 2022-04-29 | — | — | CN | disclosed |