Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenazine SCHEMBL27991538 | 0.85 | MAPT (0.65) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29364974 | 0.84 | MAPT (0.62) | MAPTALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL103601 | 0.84 | MAPT (0.62) | MAPTALDH1A1KDM4ECYP1A2HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27821564 | 0.82 | MAPT (0.59) | MAPTALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL11011451 | 0.82 | MAPT (0.59) | MAPTALDH1A1KDM4ECYP1A2HSD17B10 | |
| Water SCHEMBL27864881 | 0.82 | MAPT (0.59) | MAPTALDH1A1KDM4ECYP1A2HSD17B10 | |
| Formamide SCHEMBL1839803 | 0.80 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ECYP1A2ERN1 | |
| Hydrochloric Acid SCHEMBL28590789 | 0.79 | MAPT (0.56) | MAPTALDH1A1KDM4ECYP1A2HSD17B10 | |
| Formamide SCHEMBL28060876 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ECYP1A2ERN1 | |
| SCHEMBL2023434 | 0.77 | ERN1 (0.49) | MAPTALDH1A1KDM4ECYP1A2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |