Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121384 | 1.00 | STING1 (0.63) | STING1CYP3A4 | |
| SCHEMBL22121390 | 0.95 | STING1 (0.57) | STING1CYP3A4 | |
| SCHEMBL30823045 | 0.93 | STING1 (0.56) | STING1CYP3A4 | |
| SCHEMBL22121334 | 0.90 | STING1 (0.50) | STING1CYP3A4 | |
| SCHEMBL22121483 | 0.88 | STING1 (0.51) | STING1CYP3A4 | |
| SCHEMBL29689511 | 0.87 | STING1 (0.50) | STING1 | |
| SCHEMBL22937441 | 0.87 | STING1 (0.50) | STING1 | |
| SCHEMBL28751947 | 0.87 | STING1 (0.50) | STING1 | |
| SCHEMBL23077417 | 0.86 | STING1 (0.53) | STING1 | |
| SCHEMBL23077419 | 0.86 | STING1 (0.53) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585623-A | Bis [ N- ((5-carbamoyl) -1H-benzo [ d ] imidazol-2-yl) pyrazole-5-carboxamide ] derivatives and related compounds as STING (interferon gene stimulator) agonists for the treatment of cancer | 梅尔莎纳医疗公司 | 2022-06-03 | — | — | CN | disclosed |