SCHEMBL30823045

SCHEMBL30823045

COc1cccc2nc(N)n(C/C=C/Cn3c(N)nc4cc(C(N)=O)cc(OCCCO)c43)c12

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.56
▸ CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28941702 0.93 STING1 (0.63) STING1CYP3A4
SCHEMBL22121384 0.93 STING1 (0.63) STING1CYP3A4
SCHEMBL19436570 0.91 STING1 (0.47) STING1CYP3A4
SCHEMBL28919114 0.91 STING1 (0.47) STING1CYP3A4
SCHEMBL22121390 0.88 STING1 (0.57) STING1CYP3A4
SCHEMBL22937441 0.84 STING1 (0.50) STING1
SCHEMBL28751947 0.84 STING1 (0.50) STING1
SCHEMBL29689511 0.84 STING1 (0.50) STING1
SCHEMBL22121334 0.83 STING1 (0.50) STING1CYP3A4
SCHEMBL23077417 0.81 STING1 (0.53) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11939343-B2 Sting agonist compounds and methods of use MERSANA THERAPEUTICS, INC. (US) 2024-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11939343-B2 Sting agonist compounds and methods of use STING1, IRF3, MAVS STING1 1/4885CYP3A4 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback