Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768893 | 0.85 | PTGDR2 (0.50) | PTGDR2CYP2C9AKR1B1 | |
| SCHEMBL2769558 | 0.84 | PTGDR2 (0.40) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL27734984 | 0.79 | PTGDR2 (0.55) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL2769315 | 0.79 | PTGDR2 (0.37) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL2771707 | 0.78 | PTGDR2 (0.36) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL27734897 | 0.77 | MEN1 (0.42) | PTGDR2CYP2C9AKR1B1MEN1KMT2A | |
| SCHEMBL27722499 | 0.77 | PTGDR2 (0.43) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL27714352 | 0.77 | PTGDR2 (0.35) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL27714373 | 0.73 | PTGDR2 (0.38) | PTGDR2PTGS2CYP2C9AKR1B1MEN1 | |
| SCHEMBL4636153 | 0.72 | L3MBTL1 (0.41) | PTGDR2PTGS2CYP2C9AKR1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243086-A | Indolizine derivatives and their use as CRTH2 antagonists | ARGENTA DISCOVERY LTD (GB) | 2008-08-13 | — | — | CN | disclosed |