Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.51 |
| ▸ | MMP13 | P45452 | 12/20 | 0.51 |
| ▸ | MMP9 | P14780 | 11/20 | 0.51 |
| ▸ | MMP3 | P08254 | 10/20 | 0.51 |
| ▸ | MMP7 | P09237 | 9/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770182 | 0.86 | MMP1 (0.62) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2690125 | 0.84 | MMP1 (0.58) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2690128 | 0.84 | MMP1 (0.58) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2439791 | 0.77 | MMP1 (0.56) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2440351 | 0.76 | MMP1 (0.65) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2440109 | 0.76 | MMP1 (0.55) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2443580 | 0.76 | MMP1 (0.55) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2437809 | 0.75 | MMP1 (0.56) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2440130 | 0.75 | MMP1 (0.54) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL2443796 | 0.75 | MMP1 (0.53) | MMP1MMP13MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472902-A | Novel piperazine compounds and their use as HCV polymerase inhibitors | JAPAN TOBACCO INC (JP) | 2009-07-01 | — | — | CN | disclosed |