SCHEMBL28944641

SCHEMBL28944641

C=CCC([O])(CN)CC=C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3262699 0.69
SCHEMBL361437 0.69 ALDH1A1 (0.41) ALDH1A1
SCHEMBL10881991 0.69 ALDH1A1 (0.41) ALDH1A1
Hydrochloric Acid SCHEMBL23277159 0.67 ALDH1A1 (0.39) ALDH1A1
SCHEMBL368093 0.67 ALDH1A1 (0.39) ALDH1A1
SCHEMBL11006129 0.67
Bromide SCHEMBL11016663 0.67 ALDH1A1 (0.39) ALDH1A1
SCHEMBL9308212 0.65
SCHEMBL20710933 0.65 ALDH1A1 (0.37) ALDH1A1
SCHEMBL9453291 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101528231-A Use of PI3K and MEK modulators in the treatment of cancer EXELIXIS INC (US) 2009-09-09 CN disclosed