Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781989 | 0.92 | MKNK2 (0.34) | MAPTCDC7CDK2 | |
| SCHEMBL27772599 | 0.86 | PDE6D (0.35) | MAPT | |
| SCHEMBL28785086 | 0.83 | CDC7 (0.35) | CDC7CDK2 | |
| SCHEMBL28781970 | 0.83 | KMO (0.36) | MAPTCDC7CDK2 | |
| SCHEMBL27793932 | 0.82 | MAPT (0.36) | MAPT | |
| SCHEMBL27772686 | 0.81 | PIM3 (0.41) | — | |
| SCHEMBL27772708 | 0.80 | HTT (0.35) | MAPT | |
| SCHEMBL28785080 | 0.80 | KDM4E (0.38) | MAPT | |
| SCHEMBL27772584 | 0.79 | SLC22A12 (0.38) | CDC7CDK2 | |
| SCHEMBL28785082 | 0.78 | FFAR4 (0.39) | CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646653-A | Fused ring compounds as partial agonists of ppar-gamma | TAKEDA PHARMACEUTICAL JP | 2010-02-10 | — | — | CN | disclosed |