Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.37 |
| ▸ | ATP4B | P51164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27173117 | 0.88 | APP (0.48) | APPMAPTGLAGAA | |
| SCHEMBL23364372 | 0.88 | PAX8 (0.45) | APPMAPTGLAGAA | |
| SCHEMBL29453173 | 0.88 | PAX8 (0.45) | APPMAPTGLAGAA | |
| SCHEMBL26510486 | 0.88 | PAX8 (0.45) | APPMAPTGLAGAA | |
| SCHEMBL28944763 | 0.87 | APP (0.43) | APPMAPTGLAGAA | |
| SCHEMBL26510426 | 0.85 | PAX8 (0.45) | APPMAPTGLAGAA | |
| SCHEMBL26510490 | 0.85 | PAX8 (0.45) | APPMAPTGLAGAA | |
| SCHEMBL26510408 | 0.84 | PAX8 (0.46) | APPMAPTGLAGAA | |
| SCHEMBL27173169 | 0.83 | APP (0.46) | APPMAPTGLAGAA | |
| SCHEMBL29876970 | 0.81 | PAX8 (0.45) | APPMAPTGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728071-A | Compound for degrading TAU protein aggregate and application thereof | 新旭生技股份有限公司 | 2022-07-08 | — | — | CN | disclosed |