Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | F7 | P08709 | 3/20 | 0.51 |
| ▸ | F3 | P13726 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290199 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL289450 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL3685317 | 0.98 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL3685319 | 0.98 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL3699857 | 0.95 | ALDH1A1 (0.51) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL3699859 | 0.95 | ALDH1A1 (0.51) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL18944784 | 0.91 | PPARG (0.53) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL15930625 | 0.89 | ALDH1A1 (0.49) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL2784824 | 0.89 | ALDH1A1 (0.49) | ALDH1A1CYP19A1PPARGF7F3 | |
| SCHEMBL3700269 | 0.89 | ALDH1A1 (0.49) | ALDH1A1CYP19A1PPARGF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427415-A1 | POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS | Pronova BioPharma Norge AS (NO) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128401-A1 | POLYUNSATURATED FATTY ACIDS FOR THE TREATMENT OF DISEASES RELATED TO CARDIOVASCULAR, METABOLIC AND INFLAMMATORY DISEASE AREAS | PRONOVA BIOPHARMA NORGE AS (NO) | 2010-11-11 | — | — | WO | claimed |