Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KIF20A | O95235 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537968 | 1.00 | KMT2A (0.69) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL28791207 | 0.87 | KDM4E (0.74) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL29538396 | 0.87 | KDM4E (0.74) | KMT2AKDM4EPKMALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL28993938 | 0.86 | KDM4E (0.72) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL18060305 | 0.83 | ALDH1A1 (0.64) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL18060306 | 0.83 | ALDH1A1 (0.64) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL28791206 | 0.83 | MAPT (0.63) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL8939662 | 0.81 | MCL1 (0.68) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL8939664 | 0.81 | MCL1 (0.68) | KMT2AKDM4EPKMALDH1A1POLB | |
| SCHEMBL18083145 | 0.79 | KMT2A (0.62) | KMT2AKDM4EPKMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507158-B | Pleuromutilin alpha-cyano cinnamic acid ester compounds with drug-resistant bacteria resisting activity and preparation method and application thereof | 广东医科大学附属医院 | 2023-04-28 | — | — | CN | disclosed |
| CN-114507158-A | Pleuromutilin alpha-cyano cinnamate compounds with drug-resistant bacterium resisting activity and preparation method and application thereof | 广东医科大学附属医院 | 2022-05-17 | — | — | CN | disclosed |