Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 5/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211882 | 0.82 | SLC1A1 (0.54) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL3211873 | 0.82 | SLC1A1 (0.54) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL5972960 | 0.82 | SLC1A1 (0.54) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL5972954 | 0.82 | SLC1A1 (0.54) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL1443814 | 0.81 | TAAR1 (0.46) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| Hydrochloric Acid SCHEMBL3064814 | 0.81 | SLC1A1 (0.53) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL28455100 | 0.79 | PNMT (0.62) | TAAR1IDO1AGXTCTSSCTSK | |
| SCHEMBL16078805 | 0.79 | TAAR1 (0.47) | TAAR1IDO1CTSSCTSK | |
| SCHEMBL2683335 | 0.79 | SLC1A1 (0.46) | SLC1A1TAAR1IDO1AGXTDPP4 | |
| SCHEMBL8495801 | 0.79 | MIF (0.46) | SLC1A1TAAR1IDO1AGXTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620860-B | Preparation method of furosemide | 济南健丰化工有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-111620860-A | Preparation method of furosemide | 苏州明锐医药科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-111620860-B | Preparation method of furosemide | 济南健丰化工有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111620860-A | Preparation method of furosemide | 苏州明锐医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |