Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945297 | 0.96 | KDM4E (0.52) | KDM4EFLT3PDE4BALDH1A1CYP2D6 | |
| SCHEMBL21101774 | 0.83 | CA12 (0.59) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22215820 | 0.82 | KDM4E (0.57) | KDM4EFLT3ALDH1A1CYP2D6MEN1 | |
| SCHEMBL24436737 | 0.80 | ALDH1A1 (0.58) | KDM4EFLT3ALDH1A1CYP2D6MEN1 | |
| SCHEMBL1067955 | 0.80 | KDM4E (0.72) | KDM4EPDE4BALDH1A1CYP2D6MEN1 | |
| SCHEMBL28663584 | 0.78 | MAPK1 (0.56) | KDM4EPDE4BMEN1KMT2AMAPT | |
| SCHEMBL28945284 | 0.76 | MEN1 (0.53) | KDM4EALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL27529057 | 0.76 | CA12 (0.53) | KDM4EALDH1A1MEN1KMT2APTGS1 | |
| SCHEMBL23757425 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL14907128 | 0.75 | KDM4E (0.74) | KDM4EPDE4BALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515588-A | Macrocyclic ULK1/2 inhibitors | 萨克生物研究学院 | 2022-12-23 | — | — | CN | disclosed |