SCHEMBL28945892

SCHEMBL28945892

FC(F)C(F)C(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8358141 0.80
SCHEMBL30387935 0.77
SCHEMBL339701 0.73
SCHEMBL30388556 0.72 ALDH1A1 (0.35)
SCHEMBL9861662 0.72
SCHEMBL652264 0.72
SCHEMBL20544042 0.72
SCHEMBL28939826 0.69
SCHEMBL13147887 0.69
SCHEMBL37487 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466704-A Preparation method of 1, 2-dichloro-3, 3-trifluoropropene 西安近代化学研究所 2024-01-30 CN claimed
CN-117342922-A Method for preparing 2, 3-tetrafluoropropene and 1, 3-tetrafluoropropene 西安近代化学研究所 2024-01-05 CN claimed
CN-117342926-A Method for synthesizing trans-1, 2-dichloro-3, 3-trifluoropropene 西安近代化学研究所 2024-01-05 CN claimed
CN-117466704-A Preparation method of 1, 2-dichloro-3, 3-trifluoropropene 西安近代化学研究所 2024-01-30 CN disclosed
CN-117466704-A Preparation method of 1, 2-dichloro-3, 3-trifluoropropene 西安近代化学研究所 2024-01-30 CN disclosed
CN-117342922-A Method for preparing 2, 3-tetrafluoropropene and 1, 3-tetrafluoropropene 西安近代化学研究所 2024-01-05 CN disclosed
CN-117342926-A Method for synthesizing trans-1, 2-dichloro-3, 3-trifluoropropene 西安近代化学研究所 2024-01-05 CN disclosed
CN-116120149-B Method for preparing fluorine-containing alkyne by dehydrohalogenating saturated halogenated hydrocarbon 北京宇极科技发展有限公司 2023-07-14 CN disclosed
CN-116120149-A Method for preparing fluorine-containing alkyne by dehydrohalogenating saturated halogenated hydrocarbon 北京宇极科技发展有限公司 2023-05-16 CN disclosed
CN-111807923-B Preparation process of 1, 1-dichloro-3, 3-trifluoropropene 浙江省化工研究院有限公司 2022-11-15 CN disclosed