Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945891 | 0.86 | KDM4E (0.58) | KDM4ETDP1MAPK1ALDH1A1USP2 | |
| SCHEMBL20509552 | 0.81 | ELANE (0.58) | KDM4ETDP1MAPK1ALDH1A1USP2 | |
| SCHEMBL27041281 | 0.81 | ELANE (0.58) | KDM4ETDP1MAPK1ALDH1A1USP2 | |
| SCHEMBL24792433 | 0.74 | KDM4E (0.67) | KDM4ETDP1MAPK1ALDH1A1USP2 | |
| SCHEMBL1013586 | 0.74 | IP6K1 (0.62) | KDM4EMAPK1ELANECTSVCTSL | |
| SCHEMBL156504 | 0.74 | IP6K1 (0.62) | KDM4EMAPK1ELANECTSVCTSL | |
| SCHEMBL31715994 | 0.74 | KDM4E (0.46) | KDM4ETDP1MAPK1ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL27988350 | 0.73 | IP6K1 (0.60) | KDM4EMAPK1ELANECTSVCTSL | |
| SCHEMBL11919210 | 0.72 | GUSB (0.50) | KDM4ETDP1ELANECTSVCTSL | |
| SCHEMBL13975080 | 0.72 | ELANE (0.54) | ELANESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677701-A | Benzo heterocyclic compound and preparation method and application thereof | 昆药集团股份有限公司 | 2023-02-03 | — | — | CN | disclosed |