Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31715978 | 0.86 | LMNA (0.48) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31716946 | 0.86 | LMNA (0.44) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31716955 | 0.85 | LMNA (0.43) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31717042 | 0.85 | LMNA (0.43) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31716050 | 0.85 | LMNA (0.43) | KDM4ETDP1ROCK2METMAPK1 | |
| Hydrochloric Acid SCHEMBL31716568 | 0.84 | LMNA (0.45) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31716882 | 0.84 | MAPK1 (0.46) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31716099 | 0.83 | LMNA (0.41) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31715980 | 0.83 | LMNA (0.42) | KDM4ETDP1ROCK2METMAPK1 | |
| SCHEMBL31715976 | 0.82 | KDM4E (0.49) | KDM4EROCK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |