SCHEMBL28946005

SCHEMBL28946005

C=CCC1(Cc2ccccc2)NCCc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.37
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SIGMAR1 Q99720 10/20 0.35
TP53 P04637 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
TSHR P16473 2/20 0.33
CYP2C19 P33261 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C9 P11712 1/20 0.33
SLC22A1 O15245 1/20 0.33
PRCP P42785 1/20 0.33
BACE1 P56817 1/20 0.32
HTR2A P28223 3/20 0.32
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8817015 0.88 MEN1 (0.40) MEN1SIGMAR1HTR2AHTR2C
SCHEMBL34420059 0.87 MEN1 (0.41) MEN1SIGMAR1TP53CYP1A2CYP3A4
SCHEMBL7175933 0.87 MEN1 (0.41) MEN1SIGMAR1TP53CYP1A2CYP3A4
SCHEMBL29080999 0.74 MEN1 (0.38) MEN1SIGMAR1HTR2A
SCHEMBL175960 0.74 MEN1 (0.39) MEN1SIGMAR1HTR2A
SCHEMBL9809143 0.72 MEN1 (0.40) MEN1SIGMAR1TP53CYP1A2CYP3A4
SCHEMBL5102164 0.72 MEN1 (0.40) MEN1LMNASIGMAR1TP53CYP1A2
SCHEMBL8818814 0.71 HTR2A (0.40) MEN1LMNASIGMAR1HTR2AHTR2C
SCHEMBL27799486 0.69 MEN1 (0.38) MEN1LMNAHTTNPSR1L3MBTL1
SCHEMBL30965333 0.67 MEN1 (0.38) MEN1LMNAHTTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650824-B Chiral diol and preparation method thereof, prepared catalyst and preparation method and application thereof 合肥工业大学 2024-01-23 CN disclosed
CN-115650824-A Chiral diol and preparation method thereof, prepared catalyst, preparation method and application 合肥工业大学 2023-01-31 CN disclosed