Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556528 | 0.73 | MAPT (0.47) | EPHX1HTTHPGDKMT2AALDH1A1 | |
| SCHEMBL28352202 | 0.73 | ACHE (0.66) | EPHX1EPHX2HTTHPGDKMT2A | |
| SCHEMBL8658563 | 0.72 | HPGD (0.68) | EPHX1EPHX2HPGDKMT2APOLB | |
| SCHEMBL17557783 | 0.72 | EPHX1 (0.54) | EPHX1EPHX2HTTHPGDKMT2A | |
| SCHEMBL28355937 | 0.72 | EPHX1 (0.54) | EPHX1EPHX2HTTHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL2988817 | 0.71 | HPGD (0.56) | EPHX1EPHX2HTTHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL17557754 | 0.71 | HPGD (0.56) | EPHX1EPHX2HTTHPGDKMT2A | |
| SCHEMBL70433 | 0.69 | HPGD (0.69) | HPGDKMT2AMEN1GPR183ALDH1A1 | |
| SCHEMBL4620335 | 0.69 | HPGD (0.73) | HTTHPGDKMT2AMEN1POLB | |
| SCHEMBL23675251 | 0.68 | HPGD (0.71) | HPGDKMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |