Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23971172 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL34466985 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL2185018 | 0.94 | KMT2A (0.48) | L3MBTL1KMT2APDE4BCTSL | |
| SCHEMBL29061358 | 0.93 | L3MBTL1 (0.48) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL4104072 | 0.92 | KMT2A (0.48) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL23971170 | 0.91 | PDE4B (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL23971176 | 0.91 | PDE4B (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL3070355 | 0.89 | PDE4B (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL3070354 | 0.89 | PDE4B (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 | |
| SCHEMBL29187943 | 0.89 | PDE4B (0.49) | L3MBTL1KMT2APDE4BKLK7NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4143189-A1 | MACROCYCLIC INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115551862-A | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2022-12-30 | — | — | CN | disclosed |