Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | IL6ST | P40189 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 7/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493546 | 1.00 | PPARA (0.51) | PPARANAAAIL6STFAAHIDH1 | |
| SCHEMBL23970492 | 1.00 | PPARA (0.51) | PPARANAAAIL6STFAAHIDH1 | |
| SCHEMBL28950479 | 1.00 | PPARA (0.51) | PPARANAAAIL6STFAAHIDH1 | |
| SCHEMBL3495345 | 0.99 | PPARA (0.51) | PPARANAAAIL6STFAAHIDH1 | |
| SCHEMBL357656 | 0.96 | PPARA (0.50) | PPARANAAAIL6STFAAHIDH1 | |
| SCHEMBL357655 | 0.96 | PPARA (0.50) | PPARANAAAIL6STFAAHIDH1 | |
| SCHEMBL13295722 | 0.90 | PPARA (0.58) | PPARANAAAIL6STIDH1ABCB1 | |
| SCHEMBL28582205 | 0.90 | PPARA (0.58) | PPARANAAAIL6STIDH1ABCB1 | |
| SCHEMBL28708853 | 0.90 | PPARA (0.58) | PPARANAAAIL6STIDH1ABCB1 | |
| SCHEMBL28708851 | 0.90 | PPARA (0.58) | PPARANAAAIL6STIDH1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-115551862-A | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2022-12-30 | — | — | CN | disclosed |