Cyclohexane

Cyclohexane

SCHEMBL2895131

C1CCCCC1.CO.CO.O=C(O)c1ccc(C(=O)OCCOC(=O)c2ccc(C(=O)O)cc2)cc1.OCCO

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
LMNA P02545 3/20 0.47
ESR1 P03372 4/20 0.46
TSHR P16473 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
KDR P35968 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ESR2 Q92731 2/20 0.45
RAB9A P51151 4/20 0.44
NPC1 O15118 3/20 0.44
CYP2D6 P10635 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPK1 P28482 1/20 0.44
NR1H2 P55055 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL8344846 0.89 TDP1 (0.48) MAPTLMNAESR1TSHRTDP1
SCHEMBL8350541 0.89 TDP1 (0.48) MAPTLMNAESR1TSHRTDP1
Cyclohexane SCHEMBL22501390 0.89 TDP1 (0.48) MAPTLMNAESR1TSHRTDP1
Water SCHEMBL10717096 0.88 TDP1 (0.47) MAPTLMNAESR1TSHRTDP1
Cyclohexane SCHEMBL11609930 0.87 SERPINE1 (0.44) MAPTLMNAESR1TSHRTDP1
SCHEMBL10329337 0.85 TDP1 (0.52) MAPTLMNAESR1TSHRTDP1
SCHEMBL12446490 0.85 TDP1 (0.52) MAPTLMNAESR1TSHRTDP1
SCHEMBL22418 0.85 TDP1 (0.59) MAPTLMNAESR1TSHRTDP1
SCHEMBL31298566 0.85 TDP1 (0.59) MAPTLMNAESR1TSHRTDP1
Terephthalic Acid SCHEMBL2895134 0.85 TSHR (0.57) TSHRALDH1A1KMT2ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718733-B2 Optically clear polycarbonate polyester compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-05-18 US claimed
US-7718733-B2 Optically clear polycarbonate polyester compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-05-18 US disclosed
EP-1831309-B1 OPTICALLY CLEAR POLYCARBONATE POLYESTER COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2008-12-10 EP disclosed
US-7345116-B2 Clear polycarbonate polyester blend CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-18 US disclosed
EP-1831309-A2 OPTICALLY CLEAR POLYCARBONATE POLYESTER COMPOSITIONS General Electric Company (US) 2007-09-12 EP disclosed
US-7256228-B2 Stabilized polycarbonate polyester composition GENERAL ELECTRIC COMPANY (US) 2007-08-14 US disclosed
EP-1797136-A1 A STABILIZED POLYCARBONATE POLYESTER COMPOSITION General Electric Company (US) 2007-06-20 EP disclosed
US-20060247389-A1 Clear Polycarbonate Polyester Blend GENERAL ELECTRIC COMPANY (US) 2006-11-02 US disclosed
WO-2006073728-A2 OPTICALLY CLEAR POLYCARBONATE POLYESTER COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-07-13 WO disclosed
US-20060135690-A1 Optically clear polycarbonate polyester compositions GENERAL ELECTRIC COMPANY 2006-06-22 US disclosed
WO-2006044087-A1 A STABILIZED POLYCARBONATE POLYESTER COMPOSITION GENERAL ELECTRIC COMPANY (US) 2006-04-27 WO disclosed
US-20060074202-A1 Stabilized polycarbonate polyester composition GENERAL ELECTRIC COMPANY 2006-04-06 US disclosed
US-20050137360-A1 Clear polycarbonate polyester blend GENERAL ELECTRIC COMPANY 2005-06-23 US disclosed
EP-1544251-A1 Clear polycarbonate polyester blend GENERAL ELECTRIC COMPANY (US) 2005-06-22 EP disclosed
US-20050113534-A1 Stabilized polycarbonate polyester composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-05-26 US disclosed