Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299586 | 0.87 | CDC7 (0.61) | KDM4ETARBP2ALDH1A1PPARAPPARD | |
| SCHEMBL8341061 | 0.84 | RAB9A (0.65) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL3419091 | 0.82 | RAB9A (0.74) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL981341 | 0.80 | SMN1; SMN2 (0.71) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL3436647 | 0.78 | RAB9A (0.77) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL8867103 | 0.77 | TARBP2 (0.70) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL892234 | 0.77 | RAB9A (1.00) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL8339610 | 0.77 | TARBP2 (0.66) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL8867803 | 0.76 | TARBP2 (0.73) | RAB9AKDM4EGAASMN1; SMN2TARBP2 | |
| SCHEMBL8867051 | 0.76 | RAB9A (0.79) | RAB9AKDM4EGAASMN1; SMN2TARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |