SCHEMBL2895321

SCHEMBL2895321

FC(F)(F)c1nc(C(F)(F)F)n(Cc2cc[c]cc2Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 4/20 0.33
NR1H3 Q13133 4/20 0.33
NR1I2 O75469 1/20 0.32
NR3C1 P04150 1/20 0.32
AR P10275 1/20 0.32
RXRA P19793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2900597 0.91 NR1H2 (0.32) NR1H2NR1H3
SCHEMBL2901094 0.81 NR1H2 (0.33) NR1H2NR1H3
SCHEMBL2900479 0.77 NR1H2 (0.33) NR1H2NR1H3
SCHEMBL2904058 0.75
SCHEMBL12467743 0.75 NR1H2 (0.38) NR1H2NR1H3
SCHEMBL1834930 0.72 NR1H2 (0.36) NR1H2NR1H3
SCHEMBL2161731 0.71 NR1H2 (0.31) NR1H2NR1H3NR1I2NR3C1AR
SCHEMBL1845990 0.71 NR1H2 (0.33) NR1H2NR1H3NR1I2NR3C1AR
SCHEMBL2161175 0.70 MET (0.35) NR1H2NR1H3
SCHEMBL1838973 0.69 POLB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed