Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18870143 | 0.94 | CA12 (0.38) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL24334100 | 0.90 | CA12 (0.37) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL2057501 | 0.89 | CA1 (0.41) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL31662276 | 0.87 | CA12 (0.40) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL1644013 | 0.87 | CA12 (0.40) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL881573 | 0.86 | ALDH1A1 (0.39) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL14528019 | 0.85 | CA12 (0.37) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL1502260 | 0.85 | STAT3 (0.44) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL6002078 | 0.85 | ALDH1A1 (0.43) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL25000172 | 0.84 | CA12 (0.39) | CA12CA1CA9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951802-B1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-07-28 | — | — | EP | claimed |
| US-7649039-B2 | Blend of an uncappped polycarbonate and an arylcarboxylate-endcapped homo-or copolycarbonate that is prepared by interfacial polymerization of diol, activated carbonyl compound and an arylcarbonyl halide; decreased discoloration after exposure to gamma radiation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-01-19 | — | — | US | claimed |
| EP-1951802-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | General Electric Company (US) | 2008-08-06 | — | — | EP | claimed |
| WO-2007053305-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-10 | — | — | WO | claimed |
| US-20070100021-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-03 | — | — | US | claimed |