Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYD88 | Q99836 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205183 | 0.93 | MYD88 (0.80) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL30205153 | 0.93 | MYD88 (0.86) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL28954767 | 0.92 | MYD88 (1.00) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL28954835 | 0.86 | MYD88 (0.73) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL28954865 | 0.86 | MYD88 (0.73) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL30205170 | 0.86 | MYD88 (0.73) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL30205169 | 0.86 | MYD88 (0.73) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL28954776 | 0.83 | MYD88 (0.71) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL28954850 | 0.82 | LMNA (0.69) | MYD88LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL30205166 | 0.82 | LMNA (0.69) | MYD88LMNASMN1; SMN2PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710251-B | Medullary differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2024-05-28 | — | — | CN | claimed |
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | claimed |
| CN-115710251-B | Medullary differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | disclosed |