Soyasapogenol B

Soyasapogenol B

SCHEMBL2895626

CC1(C)CC(O)[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CCC(O)C(C)(CO)C5CC[C@]43C)[C@H]2C1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.78
PTPN1 P18031 9/20 0.71
F3 P13726 2/20 0.71
USP2 O75604 2/20 0.71
LMNA P02545 1/20 0.71
CYP3A4 P08684 1/20 0.71
USP7 Q93009 1/20 0.71
SLCO1B3 Q9NPD5 1/20 0.71
SLCO1B1 Q9Y6L6 1/20 0.71
AKR1B10 O60218 1/20 0.63
AKR1B1 P15121 1/20 0.63
TOP2A P11388 1/20 0.62
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Soyasapogenol B SCHEMBL8339201 1.00 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA
Soyasapogenol B SCHEMBL6235008 1.00 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA
Soyasapogenol B SCHEMBL12422241 1.00 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA
Soyasapogenol B SCHEMBL2895622 1.00 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA
Soyasapogenol B SCHEMBL12509509 1.00 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA
Soyasapogenol B SCHEMBL398310 1.00 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA
SCHEMBL6816904 0.92 ALOX5 (0.75) ALOX5PTPN1F3USP2LMNA
SCHEMBL6812279 0.92 ALOX5 (0.75) ALOX5PTPN1F3USP2LMNA
SCHEMBL1047280 0.92 ALOX5 (0.72) ALOX5PTPN1F3USP2LMNA
SCHEMBL6816946 0.89 ALOX5 (0.63) ALOX5PTPN1F3USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
CN-106554340-B The purposes and its isolation and purification method of monomeric compound in a kind of Chinese wistaria tumor 安徽中医药大学 2018-11-23 CN disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
CN-106554340-A The purposes and its isolation and purification method of monomeric compound in a kind of Caulis wisteriae sinensiss tumor 安徽中医药大学 2017-04-05 CN disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-2145959-A2 Triterpene Hydroxylase Meiji Seika Kaisha, Ltd. (JP) 2010-01-20 EP disclosed
US-7575892-B2 Expression vector encoding a triterpene hydroxylase polypeptide MEIJI SEIKA KAISHA, LTD. (JP) 2009-08-18 US disclosed
US-20080003639-A1 Triterpene Hydroxylase MEIJI SEIKA KAISHA, LTD. (JP) 2008-01-03 US disclosed
EP-1721983-A1 TRITERPENE HYDROXYLASE MEIJI SEIKA KAISHA LTD. (JP) 2006-11-15 EP disclosed