Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 12/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 12/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104088 | 0.89 | NR1H2 (0.51) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL29104051 | 0.89 | NR1H2 (0.51) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL21935456 | 0.89 | NR1H2 (0.48) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL18186418 | 0.89 | NR1H2 (0.48) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL18186416 | 0.89 | NR1H2 (0.48) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL16824975 | 0.89 | NR1H2 (0.48) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL29104020 | 0.89 | NR1H2 (0.51) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL38661629 | 0.87 | NR1H2 (0.48) | NR1H2NR1H3GPR119 | |
| SCHEMBL18186345 | 0.85 | MAPT (0.63) | NR1H2NR1H3LMNAMAPTALDH1A1 | |
| SCHEMBL16569609 | 0.85 | MAPT (0.63) | NR1H2NR1H3LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149939-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | Bristol-Myers Squibb Company (US) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551850-A | Small molecule inhibitors of galectin-3 | 百时美施贵宝公司 | 2022-12-30 | — | — | CN | disclosed |