Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.51 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104020 | 1.00 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL29104051 | 1.00 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL25808763 | 0.91 | NR1H2 (0.51) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL28956370 | 0.89 | NR1H2 (0.49) | NR1H2NR1H3ALDH1A1LMNAMAPT | |
| SCHEMBL16824975 | 0.88 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1LMNAMAPT | |
| SCHEMBL21935456 | 0.88 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1LMNAMAPT | |
| SCHEMBL18186416 | 0.88 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1LMNAMAPT | |
| SCHEMBL18186418 | 0.88 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1LMNAMAPT | |
| SCHEMBL29104046 | 0.87 | NR1H2 (0.48) | NR1H2NR1H3ESRRBESR1ESRRA | |
| SCHEMBL38661629 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |