Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CDC7 | O00311 | 4/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064837 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL290233 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL289907 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL290136 | 0.87 | SMN1; SMN2 (0.50) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL290379 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL290135 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL289893 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL290085 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL290226 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4ELMNACDC7DBF4 | |
| SCHEMBL289396 | 0.81 | KDM4E (0.59) | ALDH1A1KDM4ELMNACDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |