Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643771 | 0.88 | HTR6 (0.45) | HTR6NOTUMMAPTMEN1KMT2A | |
| SCHEMBL19642763 | 0.85 | HTR6 (0.41) | HTR6MAPTMAPK1MEN1KMT2A | |
| SCHEMBL15336103 | 0.77 | SLC6A2 (0.43) | HTR6NOTUMMAPK1TSHRKMT2A | |
| SCHEMBL30099065 | 0.75 | HTR6 (0.43) | HTR6NOTUM | |
| SCHEMBL19644531 | 0.72 | F12 (0.54) | — | |
| SCHEMBL19644293 | 0.72 | F12 (0.54) | — | |
| SCHEMBL13165472 | 0.71 | NOTUM (0.44) | NOTUMMAPTTSHR | |
| SCHEMBL14399667 | 0.70 | HTR6 (0.52) | HTR6 | |
| SCHEMBL13674833 | 0.68 | NOTUM (0.51) | HTR6NOTUMMAPTTSHRMEN1 | |
| SCHEMBL28279788 | 0.67 | KDM4C (0.43) | HTR6NOTUMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475530-A | For treating the aminoacyl indazole immunomodulator of autoimmune disease | 洛克菲勒大学 | 2019-03-15 | — | — | CN | disclosed |