SCHEMBL28957445

SCHEMBL28957445

CCCCCCCC[Si](CC)(OC)OCOCCCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
CES2 O00748 2/20 0.34
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
USP2 O75604 1/20 0.33
PRKD3 O94806 1/20 0.32
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCI P41743 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32
PRKCZ Q05513 1/20 0.32
PRKCD Q05655 1/20 0.32
PRKD1 Q15139 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852512 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL27581758 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL8852152 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL27832436 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL4733099 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL5573901 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL5573932 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL27832274 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL8852138 0.79 LMNA (0.41) MEN1THRBKMT2AALDH1A1LMNA
SCHEMBL28853041 0.79 LMNA (0.44) HTTMEN1THRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666399-A Hardcoat film constituent and hardcoat film 奇美实业股份有限公司 2019-04-23 CN disclosed