Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305492 | 0.83 | L3MBTL1 (0.67) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL29727188 | 0.83 | L3MBTL1 (0.67) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL29727186 | 0.83 | L3MBTL1 (0.67) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL30978278 | 0.81 | L3MBTL1 (0.69) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL13209744 | 0.81 | L3MBTL1 (0.69) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL13338300 | 0.81 | KDM4E (0.69) | MEN1KMT2ASMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL21940222 | 0.80 | GAA (0.49) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7719697 | 0.80 | L3MBTL1 (0.63) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL28164670 | 0.80 | L3MBTL1 (0.63) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL28252270 | 0.79 | L3MBTL1 (0.61) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108980-B | Preparation method of No. 4 acylated derivative of 2-methylquinoline compound | 济南大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-115108980-A | Preparation method of 4-bit acylated derivative of 2-methylquinoline compound | 济南大学 | 2022-09-27 | — | — | CN | disclosed |