SCHEMBL28958

SCHEMBL28958

O=C1N=c2[c]cccc2=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184454 0.83
SCHEMBL2033144 0.74
SCHEMBL37950 0.70 MEN1 (0.35)
Hydrochloric Acid SCHEMBL4647777 0.68 APAF1 (0.33)
Bromide SCHEMBL28523892 0.68 APAF1 (0.33)
SCHEMBL640436 0.68 APAF1 (0.33)
Water SCHEMBL11357123 0.68 APAF1 (0.33)
SCHEMBL31241401 0.68 APAF1 (0.33)
SCHEMBL3150791 0.65
SCHEMBL2145086 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3638 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024120471-A1 COMPOUNDS TARGETING MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-06-13 WO claimed
CN-117510350-A Stilbene And-1 protein degradation agent, preparation method And application thereof 中国医学科学院放射医学研究所 2024-02-06 CN claimed
CN-117327065-A Carbazole derivatives as dopamine D2/3 receptor modulators 北京大学 2024-01-02 CN claimed
WO-2023213965-A1 INHIBITORS OF CDK8 AND CDK19 UNIVERSITY OF DUNDEE (GB) 2023-11-09 WO claimed
CN-116693533-A Five-membered heteroaromatic ring type gin-MLL interaction inhibitor, preparation method and medical application thereof 成都硕德药业有限公司 2023-09-05 CN claimed
US-20230143552-A1 DOPAMINE D2 RECEPTOR LIGANDS THE BROAD INSTITUTE, INC. (US) 2023-05-11 US claimed
WO-2023064195-A1 CGRP ANTAGONISTS FOR TREATING TRIGEMINAL NEURALGIA PFIZER IRELAND PHARMACEUTICALS (IE) 2023-04-20 WO claimed
US-20230116602-A1 MCL1 INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-04-13 US claimed
WO-2023034466-A1 CGRP ANTAGONISTS FOR TREATING PSORIASIS PFIZER IRELAND PHARMACEUTICALS (IE) 2023-03-09 WO claimed
WO-2023034467-A2 CGRP ANTAGONISTS FOR TREATING SKIN CONDITIONS PFIZER IRELAND PHARMACEUTICALS (IE) 2023-03-09 WO claimed
US-4314938-A Iminoisoindolinone pigments containing phenylazoacetoacetyl-aminophenylene groups CIBA-GEIGY CORPORATION (US) 1982-02-09 US claimed
US-4294966-A SALT FORMATION CIBA-GEIGY CORPORATION (US) 1981-10-13 US claimed
US-4231799-A MONOAZO DYES, MULTILAYER, CHARGE TRANSPORTING COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-04 US claimed
EP-0007605-A1 A process for inverting the configuration in optically active compounds and optically active intermediate compounds and their salts required therefor CIBA-GEIGY AG (CH) 1980-02-06 EP claimed
US-4166117-A HYPOTENSIVES SCIENCE UNION ET CIE (FR) 1979-08-28 US claimed
US-4131733-A PIGMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1978-12-26 US claimed
US-4074053-A Aldehydes of 2-hydroxy-naphthalene-3-carboxylic acid arylides HOECHST AKTIENGESELLSCHAFT (DT) 1978-02-14 US claimed
US-4042591-A PIGMENTS, DISPERSE DYES SANDOZ LTD. (CH) 1977-08-16 US claimed
US-4042577-A POLYESTERS, POLYAMIDES, CELLULOSE ACETATES SANDOZ LTD. (CH) 1977-08-16 US claimed
US-4041036-A NAPHTHO(1',2':5,6)-PYRANO(2,3-D)PYRIMIDINE DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-09 US claimed