SCHEMBL28958014

SCHEMBL28958014

CCC(C(=O)O)N(Br)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
GLA P06280 1/20 0.48
TSHR P16473 1/20 0.48
TP53 P04637 3/20 0.43
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
JAK2 O60674 1/20 0.37
PAX8 Q06710 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27623105 0.83 SMPD2 (0.39) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL430659 0.79 ALDH1A1 (0.46) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL430660 0.79 ALDH1A1 (0.46) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL9324872 0.78 TSHR (0.48) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL28571251 0.78 ALDH1A1 (0.44) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL28958055 0.78 ALDH1A1 (0.44) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL6550464 0.78 ALDH1A1 (0.44) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL6136294 0.76 ALDH1A1 (0.45) ALDH1A1GLATSHRTP53KMT2A
Hydrochloric Acid SCHEMBL2313635 0.76 ALDH1A1 (0.43) ALDH1A1GLATSHRTP53KMT2A
SCHEMBL1984000 0.75 ALDH1A1 (0.42) ALDH1A1GLATSHRTP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557888-A Method for preparing quinoline derivative by photocatalysis of N-aryl glycine ester 安徽理工大学 2023-01-03 CN disclosed