SCHEMBL28958193

SCHEMBL28958193

Cc1ccccc1CC=S

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.46
ACHE P22303 2/20 0.41
TSHR P16473 1/20 0.41
CHRM2 P08172 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
MAPT P10636 1/20 0.39
P2RX7 Q99572 2/20 0.39
KMT2A Q03164 2/20 0.38
CYP2A13 Q16696 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CTBP2 P56545 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1988589 0.78 TAAR1 (0.48) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL6085811 0.76 TAAR1 (0.46) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL29767673 0.76 TAAR1 (0.46) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL1610053 0.76 TAAR1 (0.46) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL87998 0.76 GABRA1 (0.47) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL168282 0.76 TAAR1 (0.46) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL7572072 0.74 GABRA1 (0.45) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL16167522 0.74 TAAR1 (0.56) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL16681697 0.74 GABRA1 (0.45) TAAR1ACHETSHRCHRM2PTGS1
SCHEMBL1276610 0.74 TAAR1 (0.56) TAAR1ACHETSHRCHRM2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed