Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331751 | 1.00 | HSD17B10 (0.55) | HSD17B10CYP1A2GAACYP2C9PKM | |
| SCHEMBL29452937 | 1.00 | HSD17B10 (0.55) | HSD17B10CYP1A2GAACYP2C9PKM | |
| SCHEMBL25331749 | 1.00 | HSD17B10 (0.55) | HSD17B10CYP1A2GAACYP2C9PKM | |
| SCHEMBL16244379 | 0.84 | MITF (0.50) | HSD17B10CYP1A2GAACYP2C9CYP2C19 | |
| SCHEMBL11713591 | 0.83 | HSD17B10 (0.52) | HSD17B10CYP1A2GAACYP2C9PKM | |
| SCHEMBL29530691 | 0.83 | MITF (0.52) | HSD17B10CYP1A2GAAMITFKDM4E | |
| SCHEMBL27235801 | 0.83 | MITF (0.52) | HSD17B10CYP1A2GAAMITFKDM4E | |
| SCHEMBL20535471 | 0.83 | MITF (0.52) | HSD17B10CYP1A2GAAMITFKDM4E | |
| SCHEMBL20535473 | 0.83 | MITF (0.52) | HSD17B10CYP1A2GAAMITFKDM4E | |
| SCHEMBL7821372 | 0.81 | TDP1 (0.57) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494439-B | Chiral biphenyl diphosphine ligand and preparation method thereof | 帝斯曼知识产权资产管理有限公司 | 2022-11-08 | — | — | CN | disclosed |