SCHEMBL28958468

SCHEMBL28958468

CC(C)(C)c1cccc(OSOc2cccc(C(C)(C)C)c2C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.40
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
ALDH1A1 P00352 5/20 0.34
TDP1 Q9NUW8 3/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 3/20 0.31
GAA P10253 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28905579 0.81 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL8733235 0.79 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL4336477 0.78 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL28426083 0.78 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL303584 0.76 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL30302998 0.76 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL1889316 0.76 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL29444949 0.76 CA2 (0.40) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL304569 0.75 CA2 (0.57) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL29516118 0.74 CA2 (0.39) CA2GABRA1GABRB2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382652-B Resistance regulator 株式会社大阪曹达 2023-02-28 CN disclosed